What Post-Approval Studies Mean for Alzheimer’s Drugs

Post-approval studies confirm whether Alzheimer's drugs work in real patients—and can result in withdrawal if trials fail to prove benefit.

Post-approval studies confirm whether Alzheimer's drugs work in real patients—and can result in withdrawal if trials fail to prove benefit.

Daily function measures like CDR-SB and ADAS-Cog are the regulatory currency that determines which dementia drugs get FDA approval.

Families observe treatment changes doctors miss between appointments—tracking at home can guide medication decisions when documented systematically.

Families observe daily patterns that doctors can't—if they track changes systematically, those observations shape how Alzheimer's treatments are adjusted.

Passive monitoring technology reveals intimate patterns of behavior, but most people don't realize what data is collected or who can access it.

Your smartwatch may notice walking, sleep, and routine changes years before a memory test would. Here's what the research shows.

Smartphones can track memory changes through regular cognitive tests and behavioral metrics, helping people spot decline early—but they're not a diagnosis tool, and limitations are real.

Home cognitive apps can track changes in processing speed and memory, but they're not designed to diagnose dementia or catch all meaningful cognitive decline.

AI tools can now detect dementia earlier and support caregivers in real time—but families need to understand their real benefits, limits, and privacy risks.

Yes, standard dementia testing tools can and do miss dementia in some communities. The most widely used cognitive screening instruments, including the...