NIA’s 2026 Late-Life Depression and Dementia Workshop: Questions Adults With Memory Concerns Can Ask About the Research

Learn what questions to ask your doctor about mood, memory, and dementia risk after NIA's 2026 workshop.

NIA's 2026 workshop on late-life depression and dementia examines how depression in older adults relates to Alzheimer's disease and related dementias, or AD/ADRD. Adults with memory concerns can use its focus on mechanisms and precision medicine to ask clearer questions about symptoms, risk, and care. The Division of Neuroscience hosts the NIA Division of Neuroscience workshop page titled "Late-life depression and AD/ADRD interface: Understanding mechanisms to move towards precision medicine." A University of Wisconsin newsletter lists the event as an NIA and National Institute of Mental Health webinar.

It gives the time as Monday, Sept. 28 at 3 p.m. under that same title.

Medical information disclaimer: This article is for general educational purposes only and does not provide medical advice, diagnosis, or treatment. Always consult a physician or other qualified health professional about symptoms, medications, tests, or treatment decisions.

Table of Contents

Why do depression and memory loss overlap?

According to the National Institute on Aging, depression is common in people with Alzheimer's and related dementias, as explained in the NIA guide on depression and older adults. The same guide says dementia can cause some of the same symptoms as depression. It also says depression can be an early warning sign of possible dementia. The National Institute on Aging also states clinical depression is not a normal part of aging, though depression is common among older adults.

A National Institute on Minority Health and Health Disparities research spotlight describes a national survey of more than 31,000 Americans age 65 and older from 2007-2015. It found people reporting serious depression and restlessness had increased risk of Alzheimer's and related dementias, with highest prevalence in African Americans. Ask whether low mood, loss of interest, sleep change, or slowed thinking fits depression, dementia, or both. Ask what pattern in your history points one way or the other. Ask if follow-up testing or referral is warranted when symptoms persist.

What treatments can you ask about?

The National Institute of Mental Health states the primary late-life depression treatments are antidepressant medication and psychotherapy. It reserves electroconvulsive therapy and other brain-stimulation therapies for severe or treatment-resistant cases.

Ask which option fits your health history, current drugs, and symptom severity. Ask what benefit to expect, what side effects to watch for, and when to report lack of improvement. Ask whether memory symptoms should be rechecked after mood improves.

How do you describe memory concerns clearly?

According to the National Institute on Aging, adults worried about memory should tell a doctor specifically what changed, as described in NIA advice on talking with your doctor. Vague forgetfulness makes triage harder.

A concrete before-and-after example gives the doctor a starting point. Bring that list to the visit and read from it. Ask what the example suggests and what next step it supports.

  • Name one task that changed, with a recent example
  • Contrast prior ability with current difficulty, such as balancing a checkbook before versus confusion now
  • Note when it started, how often it happens, and who else noticed it

Where can you get free information?

The National Institute on Aging says its ADEAR Center answers telephone, email, and written requests. It provides free publications on Alzheimer's and related dementias and makes referrals.

Use the center to request plain-language materials before a visit. Ask what questions help separate depression from early cognitive change. Call 800-438-4380 for help.


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Educational information only. It is not medical advice and does not replace care from a qualified clinician.