**Why Some Dementia Medications Are Taken at Night**
Dementia medications like donepezil (Aricept) are often prescribed to be taken in the evening, and there’s a good reason for this. These drugs work by boosting brain chemicals involved in memory and thinking, but they can also cause side effects like nausea or dizziness. Taking them at bedtime helps you sleep through those initial discomforts[1][4].
However, timing isn’t just about side effects—it’s also about how dementia itself affects sleep. People with dementia often experience disrupted sleep patterns, waking frequently or feeling drowsy during the day. Some dementia medications might contribute to daytime drowsiness, which can make nighttime sleep even harder[3]. By taking certain medications at night, doctors aim to align their effects with natural sleep cycles while minimizing daytime grogginess[4].
There’s another layer: research shows that some common sleep aids (like Benadryl or prescription sedatives) are linked to a higher risk of cognitive decline over time[2]. For people already managing dementia, avoiding additional medications that could worsen brain health is crucial. If a dementia medication causes insomnia or nightmares—a possible side effect mentioned in studies—doctors might adjust the timing or dose to balance benefits and risks[3][4].
In short: nighttime dosing helps manage side effects *and* works with the body’s rhythms. But because everyone responds differently, doctors often tweak schedules based on how well someone sleeps or tolerates the drug[3][4]. Always talk to your healthcare provider if a medication disrupts your rest—there are ways to adjust without losing its benefits.
