Why do dementia patients mistake night for day?

Dementia patients often mistake night for day because their internal biological clock, known as the circadian rhythm, becomes disrupted due to the disease’s impact on the brain. This disruption leads to confusion about the time of day, causing them to be restless or active during the night when they would normally be asleep. The brain areas responsible for regulating sleep-wake cycles and processing environmental cues like light and darkness are impaired, making it difficult for them to distinguish between day and night.

The circadian rhythm is a natural, roughly 24-hour cycle that tells the body when to sleep, wake, eat, and perform other vital functions. In healthy individuals, exposure to daylight helps reset this clock daily, reinforcing the difference between daytime and nighttime. However, in dementia, especially Alzheimer’s disease, the brain’s ability to interpret these cues deteriorates. The suprachiasmatic nucleus (SCN), a small region in the brain’s hypothalamus that controls circadian rhythms, can be damaged by the disease. This damage leads to a breakdown in the normal signaling that tells the body when it is time to be awake or asleep.

As a result, dementia patients may experience what is called “sundowning,” a phenomenon where confusion, agitation, and restlessness increase in the late afternoon and evening. This can cause them to become more active at night, wandering or trying to engage in daytime activities during hours when it is dark. Their minds may mistakenly believe it is daytime because the internal clock is no longer synchronized with the actual day-night cycle.

Additionally, dementia affects memory and cognitive functions, which means patients may forget the time of day or where they are. They might not recognize that it is nighttime or that it is time to sleep. This confusion is compounded by poor sleep quality common in dementia, where deep, restorative sleep phases are reduced. Without good quality sleep, patients wake up feeling tired and disoriented, further blurring the line between night and day.

Environmental factors also play a role. Poor lighting or shadows in the evening can create illusions or confusion, making it harder for dementia patients to interpret their surroundings correctly. They may mistake shadows for obstacles or people, increasing anxiety and restlessness. Lack of exposure to natural light during the day can worsen circadian rhythm disruption, making it even more difficult for them to maintain a normal sleep-wake pattern.

Other factors contributing to this confusion include physical discomfort, hunger, the need to use the bathroom, or a desire for social interaction. Because dementia impairs communication, patients may not be able to express these needs clearly, leading to nighttime wandering or agitation as they try to fulfill these unmet needs.

Caregivers often find that establishing a consistent daily routine, ensuring exposure to bright light during the day, and creating a calm, dark, and quiet environment at night can help reduce confusion and improve sleep patterns. Avoiding caffeine and alcohol late in the day and encouraging physical activity can also support better regulation of the sleep-wake cycle.

In essence, dementia patients mistake night for day because the disease disrupts the brain’s internal clock and cognitive abilities, impairing their ability to interpret time cues and maintain a normal sleep-wake rhythm. This leads to confusion, restlessness, and behaviors such as nighttime wandering that reflect their altered perception of day and night.