Memantine is a medication commonly used to treat moderate to severe Alzheimer’s disease. It works by blocking certain receptors in the brain that are involved in the disease’s progression. While memantine can be effective, it also comes with some side effects. Here are some of the most common ones:
**Common Side Effects:**
– **Headache:** This is one of the most frequently reported side effects, affecting about 5% of users[4].
– **Dizziness:** Many people taking memantine experience dizziness, which can make it difficult to balance or walk[3].
– **Constipation:** Some individuals may experience constipation, although it’s not as common as in other medications[4].
– **Feeling Tired or Weak:** Memantine can cause fatigue, making it hard to perform daily activities[3].
– **Trouble Sleeping:** Insomnia or difficulty falling asleep is another common side effect[3].
**Less Common Side Effects:**
– **Pain:** Some people may experience pain, which can vary in intensity[2].
– **Abnormal Crying:** Emotional changes, such as increased crying, can occur[2].
– **Leg Pain:** Pain in the legs is another less common side effect[2].
– **Fever:** A slight increase in body temperature can occur in some cases[2].
– **Increased Appetite:** Unlike many other medications, memantine can sometimes increase appetite[2].
**Serious Side Effects:**
While rare, serious side effects can include allergic reactions. Symptoms of an allergic reaction can range from mild (like a rash) to severe (such as swelling or difficulty breathing). If you experience severe symptoms, it’s crucial to seek immediate medical attention[1][5].
Overall, while memantine can have side effects, it is often well-tolerated and can be an effective part of managing Alzheimer’s disease. If you’re experiencing any side effects, it’s important to discuss them with your healthcare provider.





