What are the best therapies for ankylosing spondylitis in seniors?

Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, leading to pain, stiffness, and reduced mobility. In seniors, managing AS requires a careful, multifaceted approach because aging bodies often have additional health considerations like decreased bone density, other chronic conditions, and slower healing. The best therapies for ankylosing spondylitis in seniors focus on controlling inflammation, maintaining mobility, reducing pain, and preserving quality of life through a combination of medication, physical therapy, lifestyle adjustments, and sometimes surgery.

**Physical Therapy and Exercise** form the cornerstone of managing ankylosing spondylitis, especially in seniors. A skilled physical therapist can create a personalized program that emphasizes gentle stretching, strengthening, and posture correction. These exercises help maintain spinal flexibility, improve muscle strength around affected joints, and reduce stiffness. Low-impact activities such as swimming, yoga, Pilates, and resistance training are particularly beneficial because they minimize joint stress while promoting cardiovascular health and mental well-being. Regular movement also helps prevent the spinal fusion and deformity that AS can cause. Seniors should avoid high-impact or strenuous exercises that place excessive weight on the spine or shoulders, as these can exacerbate symptoms. Consistency is key, even during flare-ups, with modifications to intensity and duration as needed.

**Medications** play a vital role in controlling inflammation and pain in ankylosing spondylitis. Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are often the first line of treatment to reduce pain and swelling. For seniors, careful monitoring is essential because long-term NSAID use can affect kidney function and gastrointestinal health. When NSAIDs are insufficient, doctors may prescribe disease-modifying anti-rheumatic drugs (DMARDs) or biologic agents such as tumor necrosis factor (TNF) inhibitors and Janus kinase (JAK) inhibitors. These medications target the immune system to reduce inflammation more effectively. TNF inhibitors, given by injection, and oral JAK inhibitors have shown good results in controlling symptoms and slowing disease progression. Steroid injections can be used selectively to reduce localized inflammation and provide temporary relief during severe flare-ups. Medication regimens must be individualized, balancing effectiveness with potential side effects, especially considering seniors’ often complex medication profiles.

**Lifestyle Modifications** are essential for managing ankylosing spondylitis in older adults. Maintaining a healthy weight reduces stress on joints and the spine, which can lessen pain and improve mobility. A balanced diet rich in anti-inflammatory foods, calcium, and vitamin D supports bone health and may help modulate inflammation. Avoiding smoking and limiting alcohol intake are important because these habits can worsen inflammation and interfere with medication effectiveness. Good sleep hygiene is also critical, as poor sleep can amplify pain and fatigue. Seniors should be encouraged to maintain social connections and manage stress, as mental health significantly impacts chronic disease outcomes.

**Assistive Devices and Ergonomic Adjustments** can improve daily functioning and reduce discomfort. Using supportive chairs, ergonomic mattresses, and tools that minimize bending or twisting can protect the spine and joints. Walking aids or braces might be necessary for those with significant mobility limitations. Occupational therapy can help seniors adapt their home environment to reduce strain and maintain independence.

**Surgical Intervention** is generally considered a last resort for seniors with ankylosing spondylitis but may be necessary in cases of severe joint damage, spinal deformity, or neurological complications. Joint replacement surgeries, such as hip or knee replacements, can restore function and relieve pain when these joints are affected. Spinal surgeries, including decompression or fusion, are more complex and carry higher risks in older adults, so they are reserved for carefully selected cases where conservative treatments have failed.

**Regular Monitoring and Multidisciplinary Care** are crucial for seniors with ankylosing spondylitis. Because the disease can affect multiple joints and systems, ongoin