Typhoid fever is treated primarily with antibiotics, which are essential to kill the Salmonella Typhi bacteria causing the infection. The choice of antibiotic depends on local patterns of bacterial resistance but commonly includes drugs such as ciprofloxacin, azithromycin, or ceftriaxone. It is crucial to complete the entire prescribed course of antibiotics even if symptoms improve early to prevent relapse and avoid developing antibiotic resistance.
In addition to antibiotics, supportive care plays a significant role in treatment. This involves rehydration through oral fluids or intravenous (IV) fluids if dehydration is severe due to diarrhea and high fever. Patients are encouraged to consume easily digestible, soft foods that are rich in nutrients to help their body recover.
For mild cases, outpatient treatment with oral antibiotics and hydration may be sufficient. However, severe cases or those with complications like intestinal perforation require hospitalization for close monitoring and IV antibiotic administration.
Symptom management also includes using antipyretics such as paracetamol (acetaminophen) to reduce high fever and alleviate discomfort.
Because typhoid can cause serious complications if untreated—such as intestinal perforation leading to peritonitis, spread of bacteria into organs like liver or kidneys, severe dehydration from prolonged diarrhea, and mental disturbances—prompt medical attention is critical.
Even after successful treatment of symptoms, some individuals become chronic carriers who continue shedding bacteria in their feces for months or longer without symptoms themselves; this can perpetuate transmission within communities. Therefore:
– Patients should maintain strict hygiene practices during illness by washing hands thoroughly after bathroom use.
– Avoid preparing food for others until cleared by a healthcare provider.
– Follow-up testing after completing antibiotics ensures eradication of the bacteria.
Treatment regimens vary depending on drug sensitivity:
– For fully sensitive strains: azithromycin orally once daily for about 7 days is common.
– In areas where resistance exists: ceftriaxone injections or other cephalosporins may be used.
– Older drugs like chloramphenicol were once standard but now face widespread resistance; relapses can occur especially with these agents.
Hospitalization might involve IV fluids and intravenous antibiotics when oral intake isn’t possible due to severity or complications arise requiring surgical intervention (e.g., bowel perforation).
Preventive measures complement treatment efforts by reducing reinfection risk:
– Vaccination before travel or exposure reduces chances but does not guarantee full protection.
– Safe food practices include eating only well-cooked meals and drinking boiled/filtered water.
– Avoiding street food in endemic areas lowers exposure risk.
In summary: treating typhoid fever effectively requires timely use of appropriate antibiotics combined with supportive care such as hydration and nutrition management while preventing spread through hygiene measures during illness. Severe cases need hospital-level care due to potential life-threatening complications.





