Preparing for an Ocrevus infusion involves several important steps to ensure the process goes smoothly and comfortably. Ocrevus (ocrelizumab) is a medication used primarily to treat multiple sclerosis (MS), administered through intravenous (IV) infusion. Because the infusion can take several hours and may cause side effects, preparation is key.
First, **consult your healthcare team** well in advance. They will provide specific instructions tailored to your health status, including any pre-infusion medications you might need, such as antihistamines or steroids, to reduce the risk of infusion reactions. They will also explain what to expect during and after the infusion.
On the day of the infusion, **wear loose, comfortable clothing** that allows easy access to your arm for the IV. Layered clothing is a good idea because infusion centers can vary in temperature, and you might want to adjust your comfort level during the treatment.
Since Ocrevus infusions can last several hours, **plan activities to pass the time**. Bring items like a fully charged tablet or smartphone loaded with movies, TV shows, podcasts, or music playlists. Headphones are essential to avoid disturbing others. If you prefer, light work such as reading, writing, or crafts like knitting can be good distractions, but keep in mind that your arm with the IV may be less mobile.
**Bring snacks and water** to stay hydrated and maintain energy, but check with your infusion center beforehand about any dietary restrictions. Some people experience nausea or fatigue during or after the infusion, so having light snacks can help.
Arrange **transportation for after the infusion**. Because Ocrevus can cause tiredness or dizziness, it’s safer not to drive yourself home. Coordinate with a family member, friend, or a ride service.
Before the infusion, make sure you have **downloaded any digital content** you want to use, as Wi-Fi may not be available or reliable at the infusion center. Also, bring a charger or power bank if you plan to use electronic devices for a long time.
During the infusion, your vital signs will be monitored regularly to watch for any adverse reactions. If you feel unwell at any point, notify the medical staff immediately. Common side effects include mild infusion reactions like itching, rash, or fever, which can often be managed on site.
If you have any questions or concerns about the infusion process, side effects, or how to manage symptoms afterward, don’t hesitate to discuss them with your healthcare provider before your appointment. Being well-informed helps reduce anxiety and makes the experience more manageable.
In summary, preparing for an Ocrevus infusion means coordinating with your medical team, dressing comfortably, planning entertainment and snacks, arranging safe transportation, and being ready to communicate any symptoms during the treatment. This preparation helps ensure the infusion is as safe and comfortable as possible.





