Why Late Afternoon Can Be the Hardest Time for Caregivers

The combination of circadian decline and caregiver fatigue makes late afternoon a predictable crisis point in dementia care.

The combination of circadian decline and caregiver fatigue makes late afternoon a predictable crisis point in dementia care.

A new Alzheimer's drug shows the ability to stabilize cognitive function in most early-stage patients—but access and side effects complicate the picture.

Normal memory lapses differ from dementia in severity, progression, and impact on daily independence.

Alzheimer's and other dementias look different under the microscope, progress at different speeds, and respond to different treatments—understanding the distinctions matters.

Autopsy findings show why Alzheimer's drugs work in some brain regions but fail in others, reshaping expectations for treatment.

Three distinct brain diseases cause dementia—Alzheimer's, vascular dementia, and Lewy body dementia—each with different causes, symptoms, and treatment approaches.

Alzheimer's is one disease within the broader dementia category, accounting for most cases but not all, with distinct causes and progression patterns.

Most families misunderstand dementia's early signs, misconceive how medications work, and wait too long to plan.

Dementia is a syndrome describing cognitive decline; Alzheimer's is the specific brain disease causing 60-80% of dementia cases.

Extended Kisunla therapy offers sustained amyloid-targeting treatment post-initial phase, but requires ongoing monitoring and realistic expectations about disease-modifying benefit.