MicroRNAs (miRNAs) are tiny molecules, usually about 20 to 22 nucleotides long, that play a big role in controlling how genes work inside our cells. They don’t code for proteins themselves but instead regulate the production of proteins by binding…
DNA methylation plays a crucial role in the development and progression of multiple sclerosis (MS) by influencing gene expression without changing the underlying DNA sequence. This epigenetic mechanism involves adding methyl groups to DNA molecules, typically at cytosine bases in…
Multiple sclerosis (MS) and epigenetics are connected through complex interactions where epigenetic mechanisms influence how genetic and environmental factors contribute to the development and progression of MS. Epigenetics refers to changes in gene expression that do not involve alterations to…
Caloric restriction, which involves reducing daily calorie intake without causing malnutrition, has been studied for its potential effects on multiple sclerosis (MS) progression. MS is a chronic autoimmune disease where the immune system attacks the central nervous system, leading to…
Intermittent fasting (IF) is a dietary approach that cycles between periods of eating and fasting, and it has gained attention for its potential health benefits across various conditions, including multiple sclerosis (MS). MS is a chronic autoimmune disease where the…
The **circadian rhythm** plays a crucial and multifaceted role in multiple sclerosis (MS), influencing disease progression, symptom patterns, sleep quality, immune function, and overall neurological health. Circadian rhythm refers to the body’s internal 24-hour biological clock that regulates sleep-wake cycles,…
Melatonin, a hormone primarily known for regulating sleep-wake cycles, has a complex and multifaceted relationship with multiple sclerosis (MS) symptoms. MS is a chronic autoimmune disease characterized by inflammation, demyelination, and neurodegeneration in the central nervous system. The effects of…
Research on sleep disorders in multiple sclerosis (MS) patients reveals a complex and significant relationship that profoundly affects their quality of life, symptom severity, and disease progression. Sleep disturbances are notably more common in people with MS than in the…
Histamine plays a multifaceted role in the progression of multiple sclerosis (MS), primarily through its involvement in immune regulation, inflammation, and blood-brain barrier (BBB) dynamics. MS is an autoimmune disease characterized by chronic inflammation and demyelination within the central nervous…
Short-chain fatty acids (SCFAs) play a crucial role in the complex interactions between the gut microbiota and the immune system, which is especially important in diseases like multiple sclerosis (MS). MS is an autoimmune disorder where the immune system mistakenly…