## Sodium and Calcium Channel Blockers in Multiple Sclerosis: Impact on Neuroaxonal Injury Multiple sclerosis (MS) is a complex disease where the immune system mistakenly attacks the protective covering of nerve fibers, called myelin, in the central nervous system. Over…
The pipeline for remyelinating drugs targeting LINGO-1 and beyond involves a complex and evolving landscape of research and development aimed at repairing damaged myelin in neurological diseases such as multiple sclerosis (MS). LINGO-1 (Leucine-rich repeat and immunoglobulin-like domain-containing protein 1)…
Neuroprotective agents can indeed slow the progression of neurological damage through mechanisms that are independent of inflammation. While inflammation is a well-known contributor to neurodegenerative diseases, neuroprotection involves a broader range of biological processes that help preserve neuronal function and…
Menopause influences the course of multiple sclerosis (MS) and the response to therapy in several important ways, primarily through hormonal changes that affect immune function, symptom expression, and treatment effectiveness. The transition into menopause involves a significant decline in estrogen…
Paternal medication safety signals for conception in multiple sclerosis (MS) refer to the potential effects that medications taken by men with MS might have on their fertility, sperm quality, and ultimately on the health of their offspring conceived during or…
Assisted reproductive technologies (ART), which include procedures like in vitro fertilization (IVF), have become increasingly common for individuals and couples facing infertility. For women with multiple sclerosis (MS), a chronic autoimmune disease affecting the central nervous system, the intersection of…
Women with multiple sclerosis (MS) face a range of unique reproductive health considerations that intertwine the complexities of their neurological condition with the natural processes of female reproductive life. These considerations span from menstrual health and sexual function to pregnancy,…
Pediatric multiple sclerosis (MS) is a chronic neurological disease that begins in childhood or adolescence, characterized by inflammation and damage to the central nervous system. One of the most pressing questions in managing pediatric MS is whether starting **high-efficacy therapy…
Pediatric multiple sclerosis (MS) treatments can significantly influence brain development trajectories, as the disease itself and its management interact with the ongoing maturation of the central nervous system in children. Pediatric MS differs from adult-onset MS not only in clinical…
Pediatric multiple sclerosis (MS) is a rare but serious condition where the immune system mistakenly attacks the protective covering of nerves in the brain and spinal cord, starting in childhood or adolescence. While much attention is given to physical symptoms…