Sézary syndrome is a rare and aggressive type of cutaneous T-cell lymphoma, a cancer that primarily affects the skin but also involves the blood and lymph nodes. It is characterized by the uncontrolled growth of malignant T lymphocytes, a type…
Cutaneous T-cell lymphoma (CTCL) is a rare type of cancer that begins in the T cells, a kind of white blood cell that plays a crucial role in the immune system. These malignant T cells primarily accumulate in the skin,…
Merkel cell carcinoma (MCC) is a rare but aggressive form of skin cancer that requires a carefully tailored treatment approach depending on the stage and extent of the disease. The treatments for MCC are diverse and often combined to maximize…
Dermatofibrosarcoma protuberans (DFSP) is a rare type of cancer that arises from the connective tissue in the skin. It is considered a slow-growing soft tissue sarcoma, meaning it develops from cells that make up fibrous tissue beneath the skin surface.…
Hemangiopericytoma is a rare type of tumor that arises from pericytes, which are specialized cells surrounding small blood vessels. Because these tumors can occur almost anywhere in the body where capillaries exist, their signs and symptoms vary widely depending on…
Angiosarcoma is a rare and aggressive cancer that originates from the cells lining blood vessels, known as endothelial cells. Understanding what causes angiosarcoma involves looking at a complex interplay of genetic, molecular, and environmental factors that lead to the abnormal…
Kaposi sarcoma (KS) is a type of cancer that primarily affects the skin but can also involve other organs. The symptoms of Kaposi sarcoma mainly manifest as distinctive skin lesions, but they can vary depending on the extent and location…
Malignant peripheral nerve sheath tumors (MPNSTs) are rare but aggressive cancers that develop from the cells surrounding peripheral nerves. These tumors arise specifically from the protective lining of nerves, which includes Schwann cells, perineurial cells, or fibroblasts. The peripheral nerves…
Synovial sarcoma is a rare and aggressive type of soft tissue cancer that primarily affects the tissues around joints, such as muscles, tendons, and ligaments. It most commonly occurs near the knees, hips, shoulders, and other large joints but can…
Rhabdomyosarcoma is a type of cancer that develops from skeletal muscle cells that have failed to fully mature. It is a malignant tumor, meaning it grows uncontrollably and can spread to other parts of the body. Understanding what causes rhabdomyosarcoma…