Can untreated infections in newborns lead to cerebral palsy?

Can untreated infections in newborns lead to cerebral palsy? Yes, they can by causing brain damage through inflammation, reduced oxygen, or direct infection of the brain and spinal cord. Newborns have weak immune systems, making them prone to serious infections like meningitis or sepsis that harm the developing brain if not treated quickly.

Infections can start before birth or right after. During pregnancy, a mothers infection such as chorioamnionitis or group B strep can pass to the baby, sparking inflammation in the brain and cutting off oxygen supply. This raises the risk of hypoxic ischemic encephalopathy, a type of brain injury linked to cerebral palsy. After birth, bacteria from the mother or the hospital environment can cause early or late onset meningitis. In early onset, germs picked up during delivery enter the bloodstream and attack the protective layers around the brain called meninges. Late onset often hits premature babies in intensive care, where tubes or ventilators let bacteria in.

Meningitis leads to swelling that damages brain tissue. Sepsis, a body wide infection, adds more risk by spreading inflammation everywhere. Even high fevers from common bugs like influenza can scar the brain in tiny infants. Jaundice from untreated infections builds up bilirubin, a substance that turns skin yellow and poisons the brain if levels get too high.

Premature or low birth weight babies face higher dangers. Their brains have fragile blood vessels prone to bleeding, and infections worsen issues like periventricular leukomalacia, where brain areas die off. Studies show late onset sepsis boosts cerebral palsy odds in extreme preemies born before 27 weeks.

Prompt treatment cuts these risks. Antibiotics fight bacteria fast, and watching for signs like fever, poor feeding, stiff limbs, or seizures helps doctors act. Good prenatal care spots maternal infections early to protect the baby. Still, some brain injuries happen despite care due to the newborns vulnerability.

Sources
https://www.nationalbirthinjurylaw.com/what-causes-cerebral-palsy
https://www.lblaw.co.uk/medical-negligence/birth-injury/cerebral-palsy-claims/
https://childrenscerebralpalsy.com/news/
https://www.medicoexperts.com/is-cerebral-palsy-curable/
https://www.bliss.org.uk/parents/about-your-baby/medical-conditions/meningitis
https://nybirthinjury.com/birth-injuries/brain-injuries/
https://www.brewsterlaw.com/medical-malpractice/birth-injuries/
https://www.cerebralpalsyguide.com/legal/cerebral-palsy-lawsuit/california/