Aubagio, a medication used to treat multiple sclerosis (MS), can indeed cause mood changes in some people. While it is primarily prescribed to reduce relapse frequency and slow disability progression in MS, mood alterations such as depression, anxiety, irritability, or other emotional shifts have been reported as less common but possible side effects.
Mood changes with Aubagio may manifest as feelings of sadness, hopelessness, or increased irritability. These changes can sometimes be subtle or develop gradually, making them easy to overlook initially. In some cases, more severe mood disturbances like depression or anxiety may occur. It is important to recognize these symptoms early because they can affect quality of life and may require medical attention or adjustments in treatment.
The reason Aubagio can cause mood changes is related to how it works in the body. Aubagio’s active ingredient, teriflunomide, modulates the immune system to reduce inflammation in the central nervous system. Since the brain and immune system are closely connected, altering immune activity can sometimes influence brain chemistry and emotional regulation. Additionally, living with MS itself can contribute to mood disorders, making it challenging to separate the effects of the disease from those of the medication.
Besides mood changes, Aubagio is known for other side effects such as hair thinning, diarrhea, headaches, and liver enzyme abnormalities. Hair thinning, for example, is relatively common but usually mild and temporary. Gastrointestinal symptoms like diarrhea and nausea may also occur, especially early in treatment. Liver function needs to be monitored regularly because Aubagio can affect liver enzymes, which in rare cases might lead to liver damage.
If mood changes occur while taking Aubagio, it is crucial to communicate this to a healthcare provider. They can evaluate whether the mood symptoms are related to the medication, the underlying MS, or other factors such as stress or concurrent illnesses. Sometimes, mood changes can be managed with supportive therapies like counseling, lifestyle adjustments, or medications specifically targeting mood disorders. In other cases, the neurologist might consider adjusting the MS treatment plan.
People starting Aubagio are often advised to monitor their emotional well-being closely, especially during the first few months of therapy when side effects are most likely to appear. Family members and caregivers can also play a role in noticing changes in mood or behavior that the patient might not recognize themselves.
It is worth noting that not everyone taking Aubagio will experience mood changes. Many people tolerate the medication well and benefit from its effects on MS symptoms without significant emotional side effects. However, because mood changes can impact daily functioning and overall health, awareness and early intervention are key.
In summary, while Aubagio is effective for managing MS, it can cause mood changes in some individuals. These changes can range from mild irritability to more serious depression or anxiety. Close monitoring, open communication with healthcare providers, and appropriate management strategies can help address these side effects and support the patient’s overall well-being during treatment.
