Aubagio, whose active ingredient is teriflunomide, is a medication primarily used to treat multiple sclerosis (MS). When considering whether Aubagio interacts with other medications, it is important to understand that it does have several potential drug interactions that can affect its safety and effectiveness.
Aubagio can interact with a variety of medications, and these interactions may increase the risk of side effects or alter how well the drugs work. For example, combining Aubagio with certain hormonal contraceptives containing ethinyl estradiol or levonorgestrel may increase the risk of side effects, so doctors may need to adjust dosages or monitor patients more closely. Additionally, drugs that affect the liver or immune system can interact with Aubagio, as it can impact liver function and immune response.
Patients taking Aubagio should inform their healthcare providers about all medications they are using, including prescription drugs, over-the-counter medicines, supplements, and herbal products. This is crucial because some drugs, such as activated charcoal or cholestyramine, can interfere with the elimination of teriflunomide from the body if taken within the last 11 days, potentially leading to increased drug levels and toxicity.
Certain medical conditions also influence how Aubagio interacts with other medications. For instance, people with liver disease, kidney disease, or a weak immune system need to use Aubagio with caution, as these conditions can worsen or alter the drug’s effects. Patients with bone marrow problems, high potassium levels, high blood pressure, or nerve issues should also be closely monitored while on Aubagio.
Unlike some other MS treatments, Aubagio does not have well-documented interactions with alcohol or food, but it is still advisable to discuss lifestyle factors with a healthcare professional to avoid unexpected effects.
In summary, Aubagio does interact with other medications, especially those affecting liver enzymes, immune function, and hormonal balance. Careful management by healthcare providers, including thorough medication reviews and monitoring of blood tests, is essential to safely use Aubagio alongside other treatments. Patients should never start or stop any medication without consulting their doctor when taking Aubagio.
