How does inhaling plutonium dust affect the lungs?

Inhaling plutonium dust is extremely dangerous because plutonium is both chemically toxic and highly radioactive, and when its tiny particles enter the lungs, they cause severe damage over time. Plutonium dust consists of microscopic particles that, once breathed in, can lodge deep in the lung tissue, particularly in the alveoli — the tiny air sacs responsible for oxygen exchange. Because plutonium is a heavy metal and an alpha particle emitter, it poses a dual threat: chemical toxicity and intense localized radiation.

When plutonium dust settles in the lungs, it remains there for a very long time because it is insoluble and not easily cleared by the body’s natural defense mechanisms like coughing or mucus. This means the radioactive particles continuously expose the surrounding lung cells to alpha radiation. Alpha particles cannot penetrate deeply into the body but are highly damaging to cells they come into direct contact with. This radiation damages the DNA inside lung cells, causing mutations that can lead to cancer, particularly lung cancer. The radiation also causes inflammation and scarring of lung tissue, impairing lung function.

Chemically, plutonium behaves like other heavy metals, disrupting normal cellular processes. It can interfere with enzymes and proteins, leading to cell death or malfunction. The combination of chemical toxicity and radiation damage triggers chronic inflammation, which further harms lung tissue and can lead to fibrosis — a thickening and stiffening of lung tissue that reduces the lungs’ ability to expand and contract, making breathing difficult.

The health effects of inhaled plutonium dust usually develop slowly. Initially, there may be no symptoms, but over months or years, individuals may experience coughing, shortness of breath, chest pain, and increased susceptibility to lung infections. The most serious long-term consequence is the development of lung cancer, which can be fatal. Because plutonium remains in the lungs for decades, the risk of cancer persists for a lifetime after exposure.

In cases of significant inhalation, medical interventions such as lung lavage (washing out the lungs) may be attempted to remove some of the plutonium particles, but this is difficult and often only partially effective. Treatment also focuses on managing symptoms and monitoring for cancer development.

In summary, inhaling plutonium dust damages the lungs through persistent radioactive exposure and chemical toxicity, causing cell death, inflammation, scarring, and greatly increasing the risk of lung cancer. The particles lodge deep in lung tissue and remain there for years, continuously harming the lungs and posing a serious health hazard.