When a newborn baby develops jaundice, it is not uncommon and usually resolves on its own. However, in rare cases, jaundice can lead to a serious condition called kernicterus jaundice. This condition occurs when high levels of bilirubin, a yellow substance found in red blood cells, build up in a baby’s brain. In this article, we will discuss what kernicterus jaundice is, its causes, symptoms, and treatment options.
What is Kernicterus Jaundice?
Kernicterus jaundice is a type of brain damage that occurs in newborn babies due to high levels of bilirubin in the blood. Bilirubin is a product of the breakdown of red blood cells and is usually processed by the liver and excreted from the body. However, in some cases, if the liver is not mature enough to handle high levels of bilirubin, or if there is an excessive breakdown of red blood cells, the bilirubin can build up in the blood and cross into the brain.
Bilirubin is a toxic substance for brain cells, and when it accumulates in the brain, it can lead to permanent damage. The term “kernicterus” comes from the Greek word “kernikteros,” which means yellow staining. This refers to the yellow discoloration that is seen in the brain tissue affected by high levels of bilirubin.
Causes of Kernicterus Jaundice
Kernicterus jaundice is primarily caused by high levels of bilirubin in the blood. There are several risk factors that can contribute to the development of this condition. These include:
1. Premature Birth: Premature babies are at a higher risk of developing kernicterus jaundice because their liver may not be fully developed to handle bilirubin efficiently.
2. Delayed Feeding: If the baby is not breastfeeding or receiving formula milk regularly, it can lead to dehydration, which can increase the level of bilirubin in the blood.
3. Blood Type Incompatibility: When the baby’s blood type is different from the mother’s, it can cause the mother’s immune system to attack the baby’s red blood cells, leading to an increased breakdown of these cells and a high level of bilirubin.
4. Bruising During Birth: If the baby experiences bruising during delivery, it can lead to an increased breakdown of red blood cells, resulting in high levels of bilirubin.
Symptoms of Kernicterus Jaundice
The symptoms of kernicterus jaundice may vary depending on the severity of the condition and the age of the baby. In some cases, the symptoms may appear within a few hours after birth, while in others, they may take several days to show up. The most common symptoms include:
1. Yellow skin and eyes: This is a classic sign of jaundice, and it occurs due to the buildup of bilirubin in the blood.
2. Poor feeding: High levels of bilirubin can affect the baby’s appetite, leading to poor feeding and weight loss.
3. High-pitched cry: Babies with kernicterus jaundice may have a high-pitched cry due to the irritability caused by brain damage.
4. Difficulty in movement: The baby may have difficulty moving their arms and legs due to muscle stiffness.
5. Seizures: In severe cases, kernicterus jaundice can lead to seizures, which are a result of brain damage.
Treatment of Kernicterus Jaundice
If left untreated, kernicterus jaundice can lead to lifelong disabilities or even death. The treatment for this condition aims to reduce the bilirubin levels in the blood and prevent further brain damage. The most common treatment methods include:
1. Phototherapy: This involves exposing the baby’s skin to special lights that help break down the bilirubin in the blood, making it easier for the body to eliminate it.
2. Intravenous immunoglobulin (IVIg): This is a medication that helps decrease the breakdown of red blood cells, reducing the level of bilirubin in the blood.
3. Blood transfusion: In severe cases, a blood transfusion may be necessary to replace the baby’s blood with fresh, healthy blood and remove the excess bilirubin.
Prevention of Kernicterus Jaundice
Although it is not possible to prevent kernicterus jaundice entirely, there are steps that can be taken to reduce the risk of developing this condition. These include:
1. Regular checkups: It is essential for pregnant women to go for regular prenatal checkups to monitor the baby’s growth and development.
2. Early feeding: Breastfeeding or formula feeding should be started as soon as possible after birth to ensure the baby receives enough fluids, preventing dehydration and high levels of bilirubin.
3. Blood type compatibility: If the mother’s and baby’s blood types are incompatible, the mother may receive injections during pregnancy to prevent complications.
In conclusion, kernicterus jaundice is a severe condition that can lead to permanent brain damage if left untreated. It is crucial for parents to be aware of the symptoms and risk factors so they can seek medical attention promptly if needed. With proper treatment and prevention measures, this condition can be managed effectively, giving the baby the best chance at a healthy life.





