What are the signs of hepatoblastoma?

Hepatoblastoma is a rare type of liver cancer that primarily affects young children, usually under the age of three. Recognizing the signs of hepatoblastoma early is crucial because it allows for timely diagnosis and treatment, which can significantly improve outcomes. The signs of hepatoblastoma often relate to the tumor growing in the liver and affecting the child’s overall health.

One of the most noticeable signs is **abdominal swelling or a visible lump** in the belly area. Parents or caregivers might observe that the child’s tummy looks larger than usual or feels firm when touched. This swelling happens because the tumor grows inside the liver, causing it to enlarge and push outward. Sometimes, this lump can be felt by gently pressing on the abdomen.

Another common sign is **abdominal pain or discomfort**. The child may become irritable or cry more than usual, especially when the belly is touched or pressed. Since young children cannot always express what they feel, this increased fussiness or sensitivity around the stomach area can be an important clue.

Children with hepatoblastoma may also show **changes in appetite**. They might eat less than usual or refuse food altogether. This loss of appetite can lead to **weight loss or failure to gain weight** as expected for their age. Along with this, some children may experience **nausea or vomiting**, which can further reduce their food intake and cause dehydration.

A less obvious but important sign is **jaundice**, which is a yellowing of the skin and the whites of the eyes. Jaundice occurs when the liver is not functioning properly or when the tumor blocks the bile ducts, causing bile to build up in the body. This yellow tint is often easier to notice in natural light and can be a warning sign of liver problems.

Other symptoms can include **fatigue or lethargy**, where the child seems unusually tired, weak, or less active than normal. This can be due to the body’s response to cancer or the liver’s reduced ability to perform its normal functions.

In some cases, children might develop **fever** without an obvious infection, which can be a sign of the body reacting to the tumor. Additionally, **easy bruising or bleeding** may occur if the liver’s ability to produce clotting factors is impaired by the tumor.

Because hepatoblastoma affects the liver, it can sometimes cause **abnormal blood test results**, such as elevated levels of alpha-fetoprotein (AFP), a protein often produced by liver tumors. While this is not a visible sign, it is an important clue doctors use to help diagnose the condition.

In summary, the signs of hepatoblastoma in children include:

– Abdominal swelling or a noticeable lump in the belly
– Abdominal pain or tenderness
– Loss of appetite and weight loss or poor weight gain
– Nausea and vomiting
– Jaundice (yellowing of skin and eyes)
– Fatigue or lethargy
– Fever without infection
– Easy bruising or bleeding

Because these symptoms can overlap with other less serious conditions, it is important for caregivers to seek medical evaluation if they notice any persistent or unusual signs in their child. Early detection and treatment are key to managing hepatoblastoma effectively.