What causes clubfoot in infants?

Clubfoot in infants is a congenital condition where one or both feet are twisted inward and downward, making the foot appear as if it is turned upside down or pointing toward the other leg. This deformity is not simply a matter of the foot being in an unusual position; the muscles, tendons, and bones in the foot and ankle are affected structurally. Specifically, the tendons and ligaments on the inside and back of the foot and ankle are shorter than normal, while those on the outside and front are stretched out, which holds the foot in this abnormal position.

The exact cause of clubfoot is not fully understood, but it is primarily considered a genetic condition. It often runs in families, meaning if one child is born with clubfoot, there is a higher chance that another child in the family may have it as well. This genetic predisposition suggests that certain inherited factors influence the development of the foot during fetal growth. However, clubfoot is not caused by the baby’s position in the womb, which is a common misconception. The condition develops early in pregnancy, and it is related to how the muscles, tendons, and bones form and grow.

In addition to genetic factors, environmental influences may also play a role, although these are less clearly defined. Some experts believe that a combination of genetic susceptibility and environmental triggers during pregnancy could contribute to the development of clubfoot. For example, reduced movement of the fetus in the womb or other unknown factors might influence the severity or occurrence of the deformity.

Clubfoot can occur as an isolated condition, meaning the infant is otherwise healthy, or it can be associated with other medical conditions or syndromes. These include neuromuscular disorders, chromosomal abnormalities, or spinal cord malformations. When clubfoot is part of a broader syndrome, it may be more complex and require specialized treatment.

The condition affects about 1 in every 1,000 babies worldwide, and it is equally common in males and females. About half of the children with clubfoot have the condition in both feet. Because the foot cannot be straightened by simple manipulation after birth, early diagnosis and treatment are crucial to ensure the foot develops properly and the child can walk and run normally.

Clubfoot can often be detected before birth through ultrasound imaging, usually after about four months of pregnancy. This early diagnosis allows parents and doctors to prepare for treatment immediately after birth, which greatly improves the chances of successful correction.

In summary, clubfoot is caused mainly by genetic factors that affect the development of the foot’s muscles, tendons, and bones during fetal growth. Environmental factors may also contribute, but the condition is not due to the baby’s position in the womb. It can occur alone or as part of other medical conditions, and early diagnosis and treatment are essential for the best outcomes.