What are the Side Effects of Oxycodone?

Oxycodone is a powerful opioid medication used to treat moderate to severe pain. While it can be effective for pain relief, it also comes with a range of side effects that can impact both physical and mental health.

### Common Side Effects

Some of the most common side effects of oxycodone include:
– **Constipation**: This is one of the most persistent side effects, affecting about 23% to 26% of users. It can lead to serious bowel issues if not managed properly.
– **Nausea and Vomiting**: These gastrointestinal symptoms are experienced by about 23% to 27% and 12% to 14% of users, respectively.
– **Drowsiness and Dizziness**: These can affect daily activities and increase the risk of accidents.
– **Itching and Sweating**: Pruritus (itching) and hyperhidrosis (sweating) are common, affecting about 13% and 5% of users, respectively.
– **Dry Mouth**: This can lead to dental problems if not properly managed.

### Less Common Side Effects

Less common but still significant side effects include:
– **Loss of Appetite**: This can lead to weight loss and nutritional deficiencies.
– **Anxiety and Nervousness**: Some people may experience increased anxiety or nervousness.
– **Abdominal Pain and Diarrhea**: These gastrointestinal issues can be uncomfortable and disrupt daily life.
– **Urinary Retention**: Difficulty urinating can be a problem for some users.

### Serious Side Effects

While less common, some serious side effects can occur:
– **Respiratory Depression**: This is a potentially life-threatening condition where breathing becomes too slow or shallow.
– **Hormonal Changes**: Chronic use can lead to hypogonadism, which affects sex hormone levels.
– **Cardiovascular Issues**: Higher doses can lead to QTc prolongation and other heart-related problems.

### Dependence and Withdrawal

Oxycodone can lead to physical dependence, and stopping it abruptly can cause severe withdrawal symptoms, including anxiety, panic attacks, nausea, and muscle pain. Gradual tapering under medical supervision is recommended to avoid these symptoms.

In summary, while oxycodone can provide effective pain relief, it’s crucial to be aware of its potential side effects and to use it responsibly under medical guidance.