Who Should Never Take HRT: Important Contraindications

Hormone Replacement Therapy (HRT) is a treatment used to manage symptoms of menopause and other hormone imbalances. While it can be effective for many people, there are certain individuals who should avoid HRT due to potential health risks.

### Women Who Should Avoid HRT

Women with a history of **breast cancer** or **ovarian cancer** are generally advised against taking HRT. This is because hormones can potentially stimulate the growth of cancer cells. Additionally, women with **ductal carcinoma in situ (DCIS)**, a type of non-invasive breast cancer, should also avoid HRT.

Women who have experienced a **heart attack** or **stroke** are at increased risk when using HRT, especially if they have existing cardiovascular conditions. This is because certain forms of HRT, particularly oral estrogen, can increase the risk of blood clots and stroke.

Those with a history of **blood clots** should also be cautious, as HRT can further increase this risk. Women with an intact uterus who are considering estrogen-only therapy should be aware that it can increase the risk of **endometrial cancer** unless combined with progesterone.

### Men Who Should Avoid HRT

For men, HRT is typically used to address low testosterone levels. However, men with a history of **prostate cancer** should avoid HRT, as testosterone can stimulate the growth of prostate cancer cells. Men who have had a **heart attack** or **stroke** are also at increased risk due to the potential cardiovascular effects of testosterone therapy.

### General Considerations

It’s crucial for anyone considering HRT to discuss their medical history thoroughly with a healthcare provider. This includes any previous cancers, cardiovascular events, or other significant health conditions. By understanding these contraindications, individuals can make informed decisions about whether HRT is safe for them.