What are the risks of polypharmacy and how to avoid medication interactions

Polypharmacy—the use of five or more medications at the same time—is common, especially among older adults. While sometimes necessary, it can bring serious risks if not managed carefully. Here’s a simple look at what those risks are and how you can avoid dangerous medication interactions.

## What Are the Risks of Polypharmacy?

When people take many medications together, several problems can arise:

– **Adverse Drug Reactions:** The more medicines you take, the higher your chance of experiencing side effects. Some side effects can be mild, like dizziness or nausea, but others may be severe.
– **Drug Interactions:** Certain drugs don’t mix well with others. For example, taking aspirin with certain blood pressure medicines (like ACE inhibitors) can cause serious problems[1]. These interactions may lead to hospitalizations or even death in some cases[4].
– **Increased Risk of Falls and Hospitalizations:** Older adults on multiple medications are more likely to fall and end up in the hospital[4].
– **Lower Quality of Life:** People taking many medicines often report feeling worse overall and having a lower quality of life[1].
– **Prescribing Cascades:** Sometimes a medicine causes a side effect that is mistaken for a new illness. This leads to even more prescriptions being added instead of stopping or changing the original medicine[4].

## How Can You Avoid Medication Interactions?

Here are some practical steps to reduce your risk:

– **Keep an Updated Medication List:** Write down all your medicines—including over-the-counter drugs and supplements—and share this list with every doctor you see.
– **Ask About Each Medicine’s Purpose:** Make sure you know why each drug is prescribed and whether it’s still needed.
– **Regular Medication Reviews:** Ask your doctor or pharmacist to review all your medicines at least once a year. This helps catch unnecessary drugs or risky combinations early.
– **Use One Pharmacy for All Prescriptions:** If possible, fill all prescriptions at one pharmacy so the pharmacist can spot potential interactions.
– **Be Aware of Side Effects:** Report any new symptoms right away; they could be caused by an interaction rather than a new illness.

## Why Is This Important?

Polypharmacy isn’t always bad—sometimes it’s necessary for managing complex health conditions. But when not monitored closely, it increases risks like falls, hospital stays, and even death[4]. By staying informed and working closely with healthcare providers, you can help ensure that your medications do more good than harm.

Remember: More isn’t always better when it comes to medicine. Regular check-ins about what you take—and why—can make all the difference in keeping you safe and healthy as you age[2][1].