**How Mangosteen Extract Protects Against Brain Oxidation**
Oxidation in the brain can lead to serious health issues, including Alzheimer’s disease and other neurodegenerative disorders. One natural compound that has shown promise in protecting against brain oxidation is mangosteen extract. In this article, we will explore how mangosteen extract works to safeguard your brain.
### What is Mangosteen?
Mangosteen is a tropical fruit native to Southeast Asia. It has been used for centuries in traditional medicine due to its numerous health benefits. The fruit’s peel, in particular, contains powerful antioxidants that play a crucial role in protecting the brain from oxidative stress.
### Antioxidant Properties
Antioxidants are substances that neutralize free radicals, which are unstable molecules that can cause damage to cells. Mangosteen extract is rich in antioxidants, including xanthones, which are known to scavenge free radicals and reduce oxidative stress. This is evident in studies where mangosteen peel infusion normalized reactive oxygen species (ROS) levels in rats exposed to hydrogen peroxide, thereby improving liver and kidney function[2].
### How Does Mangosteen Extract Work?
When free radicals accumulate in the brain, they can lead to inflammation and damage to neurons. Mangosteen extract helps by reducing the levels of these free radicals, thereby minimizing the damage. Here are some key ways mangosteen extract protects against brain oxidation:
1. **Reduces Inflammation**: Mangosteen has been shown to decrease inflammatory biomarkers, such as C-reactive protein, by 46% in healthy adults. Chronic inflammation is a significant risk factor for neurodegenerative diseases, and mangosteen’s anti-inflammatory properties help mitigate this risk[2].
2. **Enhances Antioxidant Capacity**: The antioxidants in mangosteen extract increase the body’s overall antioxidant capacity. This means that the body is better equipped to handle oxidative stress, reducing the likelihood of brain damage[2].
3. **Improves Cognitive Function**: Studies have indicated that mangosteen extract can improve cognitive function in individuals with mild to moderate Alzheimer’s disease. The meta-analysis involving 4,974 participants revealed significant improvements in ADAS-Cog scores, suggesting that mangosteen extract may have a positive impact on cognitive outcomes[1].
### Conclusion
Mangosteen extract is a natural and effective way to protect against brain oxidation. Its rich antioxidant properties, anti-inflammatory effects, and potential to improve cognitive function make it a promising compound for neuroprotection. While more research is needed to fully understand its mechanisms, the existing evidence supports the use of mangosteen extract as a potential therapeutic agent for neurodegenerative diseases.
By incorporating mangosteen extract into your diet or supplement routine, you can help safeguard your brain against the damaging effects of oxidative stress. Always consult with a healthcare professional before adding any new supplements to your regimen.
