Virtual reality (VR) therapy is emerging as a powerful tool to enhance both balance and cognitive function in people with multiple sclerosis (MS). MS is a neurological condition that often impairs mobility, coordination, and mental processing, making everyday activities challenging.…
Closed-loop neuromodulation holds promising potential to improve mobility in people with progressive multiple sclerosis (MS) by directly modulating neural circuits involved in movement control. Progressive MS often leads to worsening motor symptoms such as muscle weakness, spasticity, and impaired coordination,…
Wearable electromyography (EMG) devices and gait analytics have become powerful tools for quantifying spasticity in people with multiple sclerosis (MS). Spasticity is a common and complex symptom in MS characterized by involuntary muscle stiffness and spasms, which disrupt normal movement…
Intrathecal therapies hold significant promise for targeting compartmentalized central nervous system (CNS) inflammation in multiple sclerosis (MS), a complex autoimmune disease characterized by immune attacks on the brain and spinal cord. Unlike systemic treatments that circulate throughout the body, intrathecal…
The role of **complement inhibition in progressive multiple sclerosis (MS)** centers on controlling an overactive immune response that contributes to ongoing nerve damage and disease progression. Complement is a part of the immune system that helps clear pathogens and damaged…
Multiple sclerosis (MS) is a complex neurodegenerative disease characterized by immune-mediated damage to the central nervous system, leading to demyelination, neuroinflammation, and progressive neurological decline. Among the many factors implicated in MS progression, abnormal iron metabolism and accumulation in the…
Iron deposition in the deep gray matter of the brain is closely linked to the progression of multiple sclerosis (MS), influencing both the physical and cognitive decline seen in patients. In MS, abnormal accumulation of iron occurs particularly in deep…
Lipid-modulating therapies hold significant promise for enhancing remyelination potential, a crucial process in repairing damaged nerve fibers in diseases like multiple sclerosis (MS) and other demyelinating conditions. Remyelination is the restoration of the myelin sheath, the protective fatty layer that…
Multiple sclerosis (MS) is a complex disease where the immune system mistakenly attacks the protective covering of nerve fibers, called myelin, in the central nervous system. This process, known as demyelination, disrupts communication between the brain and the rest of…
Deprescribing protocols have the potential to improve cognition and reduce falls in people with multiple sclerosis (MS) by carefully reducing or stopping medications that may contribute to cognitive impairment, dizziness, or balance problems. MS is a complex neurological condition often…